Comparison of selectivity for acidic pharmaceuticals

Comparison of selectivity for acidic pharmaceuticals

Comparison of selectivity for acidic pharmaceuticals

Application Number
127930
Method
HPLC
Results

Legend:
1 - sulindac 2 - suprofen 3 - ketoprofen 4 - fenoprofen 5 - ibuprofen 6 - diclofenac

Substances
sulindac; suprofen; ketoprofen; fenoprofen; ibuprofen; diclofenac
Product(s)
PhaseREFWebshop

NUCLEODUR π²

760622.30

Matrix
Sample(s)
Conditions

Eluent A: 0.1% TFA in water Eluent B: 0.1% TFA in acetonitrile Gradient: 50% B for 2.5 min, 50 - 70% B in 3.5 min, 70% B for 4 min Flow rate: 0.56 mL/min Temperature: 30 °C Injection volume: 1.0 µL

Detection
UV, 280 nm
Note
Fenoprofen and ibuprofen are separated only on NUCLEODUR π²
Author
HPLC department
Source
MACHEREY-NAGEL, Germany 2016
Disclaimer
Concerning questions to literature applications please contact the cited author/s. Chemicals mentioned in applications are not manufactured or sold by MACHEREY-NAGEL. Applications mentioned in MACHEREY-NAGEL literature or databases are provided for informational purposes only. MACHEREY-NAGEL does not warrant that all applications have been tested in MACHEREY-NAGEL laboratories using MACHEREY-NAGEL products. MACHEREY-NAGEL does not warrant the correctness of the applications.