Comparing the separation of β-blockers on NUCLEODUR Phenyl-Hexyl with competitor phases with similar modification

Comparing the separation of β-blockers on NUCLEODUR Phenyl-Hexyl with competitor phases with similar modification

Comparing the separation of β-blockers on NUCLEODUR Phenyl-Hexyl with competitor phases with similar modification

Application Number
125880
Method
HPLC
Results

Legend:
1 - atenolol 2 - metoprolol 3 - labetalol 4 - propranolol


Substances
atenolol; metoprolol; labetalol; propranolol
Product(s)
PhaseREFWebshop

NUCLEODUR Phenyl-Hexyl

760578.30

Matrix
-
Sample(s)

Each compound 1 mg/mL in eluent

Conditions
  • Eluent: 20 mmol/L KH2PO4, pH 2.5 - methanol (50:50, v/v)
  • Flow: 0.56 mL/min
  • Temperature: 25 °C
  • Injection volume: 0.5 µL
Detection
UV, 230 nm
Note
Compared to competitor columns, the best peak shapes are obtained with NUCLEODUR Phenyl-Hexyl.
Author
HPLC department
Source
MACHEREY-NAGEL, Germany 2012
Disclaimer
Concerning questions to literature applications please contact the cited author/s. Chemicals mentioned in applications are not manufactured or sold by MACHEREY-NAGEL. Applications mentioned in MACHEREY-NAGEL literature or databases are provided for informational purposes only. MACHEREY-NAGEL does not warrant that all applications have been tested in MACHEREY-NAGEL laboratories using MACHEREY-NAGEL products. MACHEREY-NAGEL does not warrant the correctness of the applications.
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